Therapeutic efficacy of marbofloxacin and ceftiofur in feedlot steers with bovine respiratory disease complex

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DOI:

https://doi.org/10.21708/avb.2022.16.4.10983

Abstract

Treatment of the bovine respiratory disease complex (BRDC) can elicit high bacterial resistance and stress to steers in a feedlot. Therefore, the present study aimed to evaluate three therapeutic protocols with long-acting antibiotics against BRDC naturally acquired in steers finished in feedlot. In a total of 80 animals finished in a feedlot, 18 steers showed clinical signs compatible with BRDC (mucopurulent nasal secretion, lung auscultation alteration, leukocytosis, and decrease of dry matter intake). These animals were randomly treated: marbofloxacin in a single dose (M1), marbofloxacin in two doses (M2), or ceftiofur in a single dose (C1) on Day 0. The clinical score of pneumonia, hemogram, daily food intake, and body weight were analyzed during 7 days. On slaughter day (Day 100), the body weight and frequency of lungs with pneumonia was evaluated. On Day 7, M2 showed absence of pneumonia, and M1 and C1 still showed a clinical score of mild pneumonia (P = 0.01). On day 2 and day 3 M2 showed a higher dry matter intake than others treatments (P = 0.05). C1 showed a lower body weight than others group on day 1 and 2 (P = 0.05). The C1 and M1 showed a higher pneumonia frequency than  M2 (P = 0.02). The M2 slaughter weight was numerically higher than the other treatments. We conclude the marbofloxacin in two doses eliminated the pneumonia´s clinical symptoms and allowed the animals to return the productivity earlier than other protocols.

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Pubblicato

2022-12-09

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Original Articles / Artigos de Pesquisa

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