Epidermal growth factor family and its role in ovarian function and embryonic development

Authors

  • Cleidson Manoel Gomes da Silva
  • Luciana Rocha Faustino
  • Juliana Jales de Hollanda Celestino
  • Ana Paula Ribeiro Rodrigues
  • José Ricardo de Figueiredo

DOI:

https://doi.org/10.21708/avb.2010.4.4.1890

Abstract

Several cellular processes, such as cell survival, proliferation, differentiation, adhesion and migration, are controlled by a variety of growth factors. Among these factors it is possible to highlight the epidermal growth factor (EGF) family, which is constituted of at least eight members, described as important mediators of ovarian function. Its action on the follicular and embryo development is mediated by tyrosina kinase transmembrane receptors that are able to interact with at least six different members of this family. This paper aims focus on the role of EGF family on follicular and embryonic development in mammals. Keywords: EGF, tyrosine kinases receptor, ovarian follicle.

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Published

2010-12-08

Issue

Section

Reviews / Revisões Bibliográficas

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